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M-020

Supelco

S(+)-Methamphetamine solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Synonym(s):

dextro-Methamphetamine

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About This Item

Empirical Formula (Hill Notation):
C10H15N
CAS Number:
537-46-2
Molecular Weight:
149.23
MDL number:
MFCD00079140
UNSPSC Code:
41116107
PubChem Substance ID:
329817739
NACRES:
NA.24

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

2-8°C

SMILES string

CN[C@@H](C)Cc1ccccc1

InChI

1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3/t9-/m0/s1

InChI key

MYWUZJCMWCOHBA-VIFPVBQESA-N

Gene Information

human ... SLC6A2(6530) , SLC6A3(6531) , SLC6A4(6532)

General description

Methamphetamine is a psychostimulant drug of the phenethylamine and amphetamine classes. Known by the street names "meth," "ice," and "glass", this Snap-N-Spike® reference solution is applicable for use in LC/MS or GC/MS applications including clinical toxicology, sports testing, forensic analysis, or urine drug testing. The dextrorotatory isomer of methamphetamine is sold under the trade name Desoxyn® for treatment of ADHD and obesity.

Application


  • Pharmacokinetic Studies of S(+)-Methamphetamine: A comprehensive study assessing the pharmacokinetic profile of S(+)-Methamphetamine highlighted its rapid absorption and metabolism, offering critical insights into its therapeutic potential and challenges in drug abuse scenarios. This research aids in optimizing dosing regimens and understanding the drug′s behavior in biological systems, essential for both clinical applications and forensic investigations (Rushton et al., 2024).

  • Pharmaceutical Applications of S(+)-Methamphetamine: Research on S(+)-Methamphetamine′s role in neurochemical processes explored its effects on neurotransmitter systems, particularly focusing on its potential therapeutic applications for attention deficit hyperactivity disorder (ADHD) and weight loss. Studies like these inform drug design and repurposing strategies, helping to mitigate abuse risks while harnessing pharmacological benefits (Pardo et al., 2024).

  • Drug Metabolism and Enantiomeric Analysis: Investigations into the metabolism of S(+)-Methamphetamine have provided detailed insights into its biotransformation pathways, crucial for developing antidotes and treatment strategies for overdose cases. This research also enhances the understanding of enantiomeric differences in drug activity, supporting the development of more targeted and effective therapeutic agents (Liut et al., 2024).

  • Clinical Trials and Neurological Research: Systematic reviews of clinical trials involving S(+)-Methamphetamine have elucidated its complex pharmacodynamics and associated behavioral effects. This information is vital for neuroscientists and pharmacologists working to develop safer and more effective CNS stimulants with fewer side effects and lower abuse potential (Barkholtz et al., 2023).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Desoxyn is a registered trademark of Abbott Laboratories Corp.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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