810195P
Avanti
18:1-12:0 NBD PS
Avanti Research™ - A Croda Brand 810195P, powder
Synonym(s):
1-oleoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphoserine (ammonium salt)
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About This Item
Recommended Products
Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (810195P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810195P
shipped in
dry ice
storage temp.
−20°C
General description
Phosphatidylserine (PS) is an acidic membrane phospholipid present in human cerebral cortex. It is majorly present in the inner leaflet of plasma membrane. NBD PS contains the fluorophore, 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) labelled at the headgroup of PS.
Application
18:1-12:0 NBD PS or 1-oleoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphoserine (ammonium salt), may be used to measure the phosphatidylserine decarboxylase (Psd1) activity.
Biochem/physiol Actions
Phosphatidylserine (PS) is involved in maintaining the nerve cell membrane and myelin sheath. Phosphatidylserine (PS) is associated with Akt, protein kinase C (PKC) and Raf-1 signaling.
Packaging
5 mL Amber Glass Screw Cap Vial (810195P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
Certificates of Analysis (COA)
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Phosphatidylserine and the human brain
Nutrition null
Lipid Homeostasis Is Maintained by Dual Targeting of the Mitochondrial PE Biosynthesis Enzyme to the ER
Developmental Cell null
Organization and dynamics of N-(7-nitrobenz-2-oxa-1, 3-diazol-4-yl)-labeled lipids: a fluorescence approach
Chemistry and Physics of Lipids null
Structural Basis for Phosphatidylethanolamine Biosynthesis by Bacterial Phosphatidylserine Decarboxylase
Structure null
Developmental cell, 44(2), 261-270 (2018-01-02)
Spatial organization of phospholipid synthesis in eukaryotes is critical for cellular homeostasis. The synthesis of phosphatidylcholine (PC), the most abundant cellular phospholipid, occurs redundantly via the ER-localized Kennedy pathway and a pathway that traverses the ER and mitochondria via membrane
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