810195P
Avanti
18:1-12:0 NBD PS
Avanti Research™ - A Croda Brand 810195P, powder
Synonym(s):
1-oleoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphoserine (ammonium salt)
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All Photos(2)
About This Item
Empirical Formula (Hill Notation):
C42H73N6O13P
CAS Number:
Molecular Weight:
901.04
UNSPSC Code:
12352211
NACRES:
NA.25
Recommended Products
Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (810195P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810195P
shipped in
dry ice
storage temp.
−20°C
General description
Phosphatidylserine (PS) is an acidic membrane phospholipid present in human cerebral cortex. It is majorly present in the inner leaflet of plasma membrane. NBD PS contains the fluorophore, 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) labelled at the headgroup of PS.
Application
18:1-12:0 NBD PS or 1-oleoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphoserine (ammonium salt), may be used to measure the phosphatidylserine decarboxylase (Psd1) activity.
Biochem/physiol Actions
Phosphatidylserine (PS) is involved in maintaining the nerve cell membrane and myelin sheath. Phosphatidylserine (PS) is associated with Akt, protein kinase C (PKC) and Raf-1 signaling.
Packaging
5 mL Amber Glass Screw Cap Vial (810195P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
Certificates of Analysis (COA)
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Lipid Homeostasis Is Maintained by Dual Targeting of the Mitochondrial PE Biosynthesis Enzyme to the ER
Jonathan R, et al.
Developmental Cell null
Phosphatidylserine and the human brain
Glade MJ and Smith K
Nutrition null
Organization and dynamics of N-(7-nitrobenz-2-oxa-1, 3-diazol-4-yl)-labeled lipids: a fluorescence approach
Mukherjee S, et al.
Chemistry and Physics of Lipids null
Structural Basis for Phosphatidylethanolamine Biosynthesis by Bacterial Phosphatidylserine Decarboxylase
Yasunori W, et al.
Structure null
Jonathan R Friedman et al.
Developmental cell, 44(2), 261-270 (2018-01-02)
Spatial organization of phospholipid synthesis in eukaryotes is critical for cellular homeostasis. The synthesis of phosphatidylcholine (PC), the most abundant cellular phospholipid, occurs redundantly via the ER-localized Kennedy pathway and a pathway that traverses the ER and mitochondria via membrane
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