SUPELCOSIL LC-DB phases are specially deactivated for basic compounds. These columns provide shorter retention, better peak shape, and higher efficiency for organic bases than can be obtained on other Type A silica reversed-phase columns.
Application
SUPELCOSIL™ LC-18-DB HPLC Column has been used for the separation of:
Analytes of pharmaceutical relevance during their analysis using LC in conjunction with principal component analysis (PCA).[1]
Loratadine in human plasma during its analysis by using HPLC combined with ultraviolet (UV) detection.[2]
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Legal Information
SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC
Determination of loratadine in human plasma by high-performance liquid chromatographic method with ultraviolet detection.
Kunicki PK.
Journal of Chromatography. B, Biomedical Sciences and Applications, 755(1-2), 331-335 (2001)
Chromatographic classification and comparison of commercially available reversed-phase liquid chromatographic columns using principal component analysis
Euerby MR and Petersson P
Journal of Chromatography A, 994(1-2), 13-36 (2003)
Aging is an independent risk factor for cardiovascular diseases, such as myocardial infarction due to ischemia-reperfusion injury (I/R) of the heart. Cytosolic thioredoxin (Trx) is a multifunctional redox protein which has antioxidant and protein disulfide reducing properties. We hypothesized that
Journal of pharmaceutical and biomedical analysis, 24(5-6), 913-920 (2001-03-15)
RGH-1756 (1-(2-methoxy-phenyl)-4-(4-[4-(6-imidazo[2,1-b]-thiazolyl)-phenoxy]-butyl)-piperazine dimethansulphonate) is a novel atypical antipsychotic candidate of Gedeon Richter Ltd. A new HPLC method has been developed and validated for the quantitative determination of RGH-1756 in dog and rat plasma. The compound and the internal standard are
A rapid, isocratic method for the determination of tryptophan in Escherichia coli fermentation broths by reversed-phase HPLC is described. Tryptophan can be measured in fermentations containing either chemically defined media or media with hydrolyzed protein supplements. The procedure was rugged
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