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48838

Supelco

Ethylene oxide solution

certified reference material, 50 mg/mL in methanol

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About This Item

Empirical Formula (Hill Notation):
C2H4O
CAS Number:
75-21-8
Molecular Weight:
44.05
MDL number:
MFCD00014482
UNSPSC Code:
12000000
PubChem Substance ID:
329757418
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grade

certified reference material
TraceCERT®

Quality Level

300

product line

TraceCERT®

CofA

current certificate can be downloaded

feature

standard type calibration

packaging

ampule of 1 mL

concentration

50 mg/mL in methanol

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
cleaning products
cosmetics
environmental
food and beverages
personal care

format

single component solution

storage temp.

2-8°C

SMILES string

C1CO1

InChI

1S/C2H4O/c1-2-3-1/h1-2H2

InChI key

IAYPIBMASNFSPL-UHFFFAOYSA-N

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General description

This substance is listed on the positive list of the EU regulation 10/2011 for plastics intended to come into contact with food. Find a list of available reference materials for compounds listed in 10/2011 here


Ethylene oxide is a toxic and flammable liquid, which can be obtained via vapor phase oxidation of ethylene.[1] It can be used in the synthesis of ethylene glycol[2], glycol ethers, surfactants and ethanolamines.[1] It is an industrially important chemical, that can be used as fumigant to sterilize dental and medical equipments.[2]

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Legal Information

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

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Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 2 - Muta. 1B - Repr. 1B - Skin Corr. 1 - STOT RE 2 - STOT SE 1

Target Organs

Eyes,Central nervous system, Nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

50.0 °F - closed cup

Flash Point(C)

10 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Propylene oxide United States Pharmacopeia (USP) Reference Standard

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76887

1,4-Dioxane

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Lees' Loss Prevention in the Process Industries: Hazard Identification, Assessment and Control (2004)
Harte J, et al.
Toxics A to Z: A Guide to Everyday Pollution Hazards (1991)
Matthieu Gatineau et al.
American journal of veterinary research, 73(10), 1665-1669 (2012-09-28)
To compare effects of sterilization with hydrogen peroxide gas plasma (HPGP), ethylene oxide, and steam on bioadhesive properties of nylon and polyethylene lines used for stabilization of canine stifle joints. Samples of a 36.3-kg test nylon leader line, 57.8-kg test
Filippo Doria et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 19(1), 78-81 (2012-12-06)
Caught in the oxirane: Naphthalene diimides conjugated to a quinone methide and an oxirane have been synthesized and investigated as selective DNA G-quadruplex alkylating agents. The oxirane derivative generates a stable adduct with a G-quadruplex and shows selective alkylation of
Guangzhi Gu et al.
Biomaterials, 34(1), 196-208 (2012-10-17)
By taking advantage of the dramatically upregulated expression of matrix metalloproteinases MMP-2 and MMP-9 in glioblastomas and the powerful transport ability of low molecular weight protamine (LMWP), we constructed an activatable low molecular weight protamine (ALMWP) and conjugated it to
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Questions

1–3 of 3 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. Please supply detailed instructions how to open and extract the chemical from its packing container. The form of the vial is not familiar to me and due to chemical's high toxicity and volatile content we need to handle it with extra care.

    1 answer

    1. The ampule may be opened by holding the top firmly with one hand and the body of the ampule in the other hand. Firmly and steadily bend the cap away from the break point or neck until the vial snaps. Dispose of the cap (containing the broken vial top) into a sharps bin. The item is intended for single-use only. Please review the product SDS for recommended personal protective equipment.
      Please see the links below to review products that may be useful in opening ampules:
      https://www.sigmaaldrich.com/product/aldrich/z693847
      https://www.sigmaaldrich.com/substance/ampulebreakercollar1234598765

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