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Key Documents

SRP0361

Sigma-Aldrich

PLK3 Polo Box Domain human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

Synonym(s):

CNK, FNK, PRK, polo-like kinase 3

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.32

biological source

human

recombinant

expressed in E. coli

Assay

≥90% (SDS-PAGE)

form

aqueous solution

mol wt

80.5 kDa

packaging

pkg of 100 μg

NCBI accession no.

NM_004073
NP_004064

UniProt accession no.

Q9H4B4

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... PLK3(1263)

General description

Human N-terminal MBP tagged Plk3 polo box domain (GenBank Accession No.NM_004073/NP_004064), amino acids 335-646 with C-terminal His-tag, MW=80.5 kDa, expressed in an E. coli expression system.

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Danger

Hazard Statements

H315,H319,H360D

Hazard Classifications

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH Annex XVII (Restriction List)

CAS No.

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Certificates of Analysis (COA)

Lot/Batch Number
5030220403

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Zhongkui Li et al.
The Journal of biological chemistry, 280(17), 16843-16850 (2005-01-27)
RelA, the p65 subunit of NF-kappaB transcription factors, plays a key role in regulation of antiapoptotic and proapoptotic responses. However, the downstream target genes regulated by RelA-NF-kappaB in the initiation of proapoptotic signaling were not identified. We previously showed that
Suqing Xie et al.
Oncogene, 23(21), 3822-3829 (2004-03-17)
MEK1, a gene product that regulates cell growth and differentiation, also plays an important role in Golgi breakdown during the cell cycle. We have recently shown that polo-like kinase (Plk3) is Golgi localized and involved in Golgi dynamics during the

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