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SML2600

Sigma-Aldrich

Melitracen hydrochloride

≥98% (HPLC)

Synonym(s):

Melitracen hydrochloride, 3-(10,10-dimethyl-9(10H)-anthracenylidene)-N,N-dimethyl-1-propanamine hydrochloride, U-24973A hydrochloride, 3-[10,10-Dimethyl-9(10H)-anthrylidene]-N,N-dimethylpropylamine hydrochloride

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10 MG
€71.60
50 MG
€231.00

€71.60

Available to ship on31 March 2025Details

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10 MG
€71.60
50 MG
€231.00

About This Item

Empirical Formula (Hill Notation):
C21H25N · HCl
CAS Number:
10563-70-9
Molecular Weight:
327.89
MDL number:
MFCD00242905
UNSPSC Code:
12352200
NACRES:
NA.77

€71.60

Available to ship on31 March 2025Details

Request a Bulk Order

Assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

H2O: 2 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

[Cl-].[N+H](CCC=C1c2c(cccc2)C(c3c1cccc3)(C)C)(C)C

InChI

1S/C21H25N.ClH/c1-21(2)19-13-7-5-10-17(19)16(12-9-15-22(3)4)18-11-6-8-14-20(18)21;/h5-8,10-14H,9,15H2,1-4H3;1H

InChI key

RADLXCPDUXFGFF-UHFFFAOYSA-N

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Biochem/physiol Actions

Melitracen is a tricyclic antidepressant (TCA) that likely exerts its in vivo efficacy similarly as imipramine and amitriptyline by inhibiting serotonin-norepinephrine reuptake.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000071928
0000071927
0000068521

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Relationship between the restriction of food intake and Melitracen, an antidepressant, in the rat.
K Shimamoto et al.
Acta Scholae Medicinalis Universitatis in Kioto, 40(1), 25-37 (1967-07-01)
Jin-Ying Li et al.
World journal of gastrointestinal endoscopy, 9(12), 590-593 (2018-01-02)
Jackhammer (hypercontractile) esophagus presents with dysphagia and chest pain. Current treatments are limited. We describe a 60-year-old man who presented with dysphagia, chest pain and heartburn for a period of 1 year. His workup showed Barrett's esophagus on endoscopy and
The pharmacological properties of melitracen (N 7001) and litracen (N 7049).
I M Nielsen et al.
Arzneimittel-Forschung, 16(2), 135-140 (1966-02-01)
Studies on the metabolism of Melitracen (N 7001) in rats.
I Eberholst et al.
Arzneimittel-Forschung, 16(7), 876-878 (1966-07-01)
Limin Wang et al.
BMC psychiatry, 15, 84-84 (2015-04-17)
Patients in chronic somatic diseases are often accompanied with depression and anxiety, remission of which may be observed in the third or fourth week after applying common antidepressant medications. We investigate the efficacy and safety of sertraline plus deanxit on
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