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SML2495

Sigma-Aldrich

MLS1082

≥98% (HPLC)

Synonym(s):

2-Cyclohexyl-10-methyl-3-phenylpyrimido[4,5-b]quinoline-4,5(3H,10H)-dione

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5 MG
€74.20
25 MG
€241.00

€74.20

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5 MG
€74.20
25 MG
€241.00

About This Item

Empirical Formula (Hill Notation):
C24H23N3O2
CAS Number:
883958-36-9
Molecular Weight:
385.46
UNSPSC Code:
12352200
NACRES:
NA.77

€74.20

In StockDetails

Assay

≥98% (HPLC)

form

powder

color

white to gray-brown

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C1C2=C(N=C(C3CCCCC3)N(C4=CC=CC=C4)C2=O)N(C)C5=CC=CC=C51

Biochem/physiol Actions

D1 dopamine receptor PAM that binds to a different allosteric site than MLS6585 (CID 2886111)
MLS1082 is a D1 dopamine receptor positive allosteric modulator (PAM) that binds to a different allosteric site than than MLS6585 (CID 2886111). When given together, they cause an additive potentiation of dopamine potency for both cAMP accumulation and β-arrestin recruitment.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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