NLR family, pyrin domain containing 6 (NLRP6) maybe part of the inflammasome. It belongs to the Nod-like receptor family and is expressed in intestinal epithelial cells.
Biochem/physiol Actions
NLR family, pyrin domain containing 6 (NLRP6) has a role in innate immunity. It also maintains intestinal homeostasis by modulating autophagy and mucus secretion. Loss of NLRP6 has been shown to hinder the production of interleukin-18 (IL-18) and enhance susceptibility to epithelial-induced injury in rats.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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Frontiers in immunology, 10, 1631-1631 (2019-08-02)
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