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RAB0657

Sigma-Aldrich

Human FABP3 / Fatty Acid-binding Protein, Heart ELISA Kit

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96 WELLS
€528.00

€528.00

Estimated to ship on16 April 2025

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96 WELLS
€528.00

About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

€528.00

Estimated to ship on16 April 2025

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type plasma
sample type cell culture supernatant(s)
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 1.5 ng/mL
standard curve range: 2.05-200 ng/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... FABP3(2170)

General description

Fatty acid-binding protein-3 (FABP3) is a small cytoplasmic protein, which is a member of the multigene family of FA-binding proteins. It is widely expressed in the heart.[1] This gene is mapped to human chromosome 1p35.[2]
SRC family belongs to non-receptor tyrosine kinases. SRC was originally identified as a transforming protein of the Rous sarcoma virus (RSV) that had enzymatic ability to phosphorylate tyrosine in protein substrates. SRC is overexpressed and activated in a large number of human malignancies and has been linked to the development of cancer and progression to distant metastases. In addition to increasing cell proliferation, a key role of SRC in cancer seems to be the ability to promote invasion and motility, functions that might contribute to tumour progression

Application

Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Fatty acid-binding protein-3 (FABP3) participates in cardiac metabolism. It plays an important role in the intracellular uptake of fatty acids and their migration towards the mitochondrial β-oxidation system.[1]

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Kit Components Also Available Separately

Product No.
Description
SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS
  • RABSTOP3ELISA Stop Solution (Item I)SDS
  • RABWASH420X Wash Buffer (Item B)SDS

Pictograms

Corrosion
GHS05

Signal Word

Warning

Hazard Statements

H290

Precautionary Statements

P234 - P390

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0242F0060
SAMPLE
0220F0060
0108F0060
1119F0060

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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Shanshan Wu et al.
European journal of medical research, 25(1), 2-2 (2020-03-18)
Acute coronary syndrome (ACS) is a serious type of cardiovascular diseases. This study aimed to investigate the expression patterns and clinical value of microRNA-145 (miR-145) in ACS patients, and further uncover the function of miR-145 in ACS rats. Quantitative real-time
The circulating level of FABP3 is an indirect biomarker of microRNA-1
Varrone F, et al.
Journal of the American College of Cardiology, 61(1), 88-95 (2013)
Louis Servaas Dolmans et al.
BMJ open, 9(10), e031774-e031774 (2019-10-20)
The diagnosis of transient ischaemic attack (TIA) based on symptoms and signs can be challenging and would greatly benefit from a rapid serum biomarker of brain ischaemia. We aimed to quantify the added diagnostic value of serum biomarkers in patients
Claire J C Huguenard et al.
Frontiers in physiology, 11, 12-12 (2020-02-23)
The differential diagnosis between mild Traumatic Brain Injury (mTBI) sequelae and Post-Traumatic Stress Disorder (PTSD) is challenging due to their symptomatic overlap and co-morbidity. As such, there is a need to develop biomarkers which can help with differential diagnosis of
Aml Gaber Mohammed Mohammed et al.
Iranian journal of kidney diseases, 13(2), 120-128 (2019-04-17)
Myocardial dysfunction is a leading cause of mortality in chronic kidney disease (CKD) children specially those on regular hemodialysis. Cardiac biomarkers play a key role for early detection of myocardial injury. We aim to clarify the prognostic role of circulating
View All Related Papers

Questions

  1. I would like to request ELISA instructions for Fatty Acid-binding Protein, Heart ELISA Kit (RAB0657). Our team has this ELISA kit but there was no instruction or information about the concentration of the standard needed for the calibration curve

    1 answer

    1. The protocol is included in the Certificate of Analysis. Please view the sample Certificate of Analysis below:
      https://www.sigmaaldrich.com/certificates/Graphics/COfAInfo/SigmaABNO/RAB0657_0242F0060.pdf

      A general ELISA protocol (not specific to this kit) can also be found via this link below:
      https://www.sigmaaldrich.com/technical-documents/protocol/protein-biology/elisa/elisa-protocols

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