P8249

Pyoverdines−Gallium (III) complex

from Pseudomonas fluorescens, >90% (HPLC)

• Synonym(s): Pyoverdines, Ga-Pv
• UNSPSC Code: 12352200

Properties

• biological source: Pseudomonas fluorescens
• Assay: >90% (HPLC)
• solubility: H₂O: ~10 mg/mL
• shipped in: wet ice
• storage temp.: −20°C

Description

Biochem/physiol Actions

Gallium-pyoverdines act as growth inhibitors of both P. fluorescens and P. aeruginosa possibly due to gallium interference with bacterial iron metabolism.

Pyoverdines, also called pseuobactins and pyoverdins, are fluorescent siderophores that have high affinity for iron (10³² M^-1), and are synthesized by fluorescent pseudomonads under iron-deficient growth conditions. Pyoverdines were shown to prevent iron toxicity produced by iron overload in hepatocyte cultures and effectively scavenges the hydroxyl and peroxyl radicals. Pyoverdines are effective in acquiring iron from transferrin and lactoferrin. Pyoverdines are also involved in the suppression of pythium-induced damping-off of tomato and promotion of growth in some higher plants.

Pyoverdines, also called pseuobactins and pyoverdins, are fluorescent siderophores that have high affinity for iron, and are synthesized by fluorescent pseudomonads under iron-deficient growth conditions.

Physical form

Supplied as a mixture containing mainly the succinic acid (MW=1231), 2-hydroxy glutaramide (MW=1260), and succinamide (MW=1230) forms of pyoverdines, bound to gallium.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable