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H3667

Sigma-Aldrich

Human Serum

Heat Inactivated, from human male AB plasma, USA origin, sterile-filtered

Synonym(s):

HI Human Plasma, HI Human Sera, HI Human Serum, human plasma, human sera, human serum

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About This Item

MDL number:
MFCD00165829
UNSPSC Code:
12352207
NACRES:
NA.71

biological source

human male plasma (Type AB)

Quality Level

300

sterility

sterile-filtered

composition

hemoglobin, ≤20 mg/dL

origin

USA origin

technique(s)

cell culture | mammalian: suitable

impurities

≤10 EU/mL endotoxin

shipped in

dry ice

storage temp.

−20°C

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General description

Serum is mostly required as a supplement to cell culture media. It contains macromolecules, carrier proteins, attachment and spreading factors, low molecular weight nutrients, and hormones and growth factors.

Application

Human Serum has been used as a supplement in culture media for monocytes. It has been used as a control in western blotting to study flightless I expression in serum.

Packaging

Packaging may vary for different batches due to short supply of the bottles used to pack this product. The presence or lack of shrink wrap around the cap of the bottle doesn’t impact product integrity/sterility of the product.

Analysis Note

Endotoxin tested

Other Notes

It is not unusual for our human serum products to be cloudy. This product is from pooled serum and cloudiness indicates that lipids are present in the serum. No clear, lipid-free human serum products are available.

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Cytoskeletal protein Flightless I inhibits apoptosis, enhances tumor cell invasion and promotes cutaneous squamous cell carcinoma progression.
Kopecki Z et al.
Oncotarget, 6, 36426-36426 (2015)
A human and animal model-based approach to investigating the anti-inflammatory profile and potential of the 5-HT2B receptor antagonist AM1030.
Palmqvist N et al.
Journal of Inflammation (London, England), 13, 20-20 (2016)
Christina Megli et al.
The Journal of experimental medicine, 218(1) (2020-09-26)
The human placenta is a dynamic organ that modulates physiological adaptations to pregnancy. To define the immunological signature of the human placenta, we performed unbiased profiling of secreted immune factors from human chorionic villi isolated from placentas at mid and
Max C Richter et al.
The EMBO journal, 37(11) (2018-04-18)
Increasing evidence suggests that synaptic functions of the amyloid precursor protein (APP), which is key to Alzheimer pathogenesis, may be carried out by its secreted ectodomain (APPs). The specific roles of APPsα and APPsβ fragments, generated by non-amyloidogenic or amyloidogenic
Anubha Seth et al.
Cellular signalling, 68, 109538-109538 (2020-01-14)
Mammalian adenylate cyclases (ACs) are pseudoheterodimers with dissimilar hexahelical membrane-anchors, isoform-specifically conserved for more than half a billion years. We exchanged both membrane anchors of the AC isoform 2 by the quorum-sensing receptor from Vibrio harveyi, CqsS, which has a
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