Glycogen is a branched polymer of glucose synthesized by animal cells for energy storage and release. It is constructed of predominantly α1→4 glycosidic bonds with branches created through α1→6 glycosidic bonds.
Application
Oyster glycogen has been used to induce inflammation and to promote extravasation of granulocytes and neutrophils in animal models after intraperitoneal injection. Glycogen also acts as a vascular permeability probe.
Other Notes
High molecular weight
Preparation Note
Prepared by a modification of Bueding, E., and Orrell, S.A., Jr., J. Biol. Chem., 236, 2854 (1961).
The Biochemical journal, 452(3), 559-573 (2013-03-30)
Escherichia coli glycogen metabolism involves the regulation of glgBXCAP operon expression and allosteric control of the GlgC [ADPG (ADP-glucose) pyrophosphorylase]-mediated catalysis of ATP and G1P (glucose-1-phosphate) to ADPG linked to glycogen biosynthesis. E. coli glycogen metabolism is also affected by glgS.
This study was undertaken to characterize the effects of monotonous training at lactate minimum (LM) intensity on aerobic and anaerobic performances; glycogen concentrations in the soleus muscle, the gastrocnemius muscle and the liver; and creatine kinase (CK), free fatty acids
The physiological relevance of acid maltase (acid α-glucosidase, an enzyme that degrades lysosomal glycogen) is well recognized in liver and muscle. In late (adult)-onset acid maltase deficiency (glycogen storage disease type II [GSD II]), glycogen accumulates inside muscular lysosomes in
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 38(2), 91-99 (2013-02-27)
Glucose is stored in skeletal muscle fibers as glycogen, a branched-chain polymer observed in electron microscopy images as roughly spherical particles (known as β-particles of 10-45 nm in diameter), which are distributed in distinct localizations within the myofibers and are
American journal of physiology. Endocrinology and metabolism, 304(8), E885-E894 (2013-03-14)
Failure of white adipose tissue to appropriately store excess metabolic substrate seems to underpin obesity-associated type 2 diabetes. Encouraging "browning" of white adipose has been suggested as a therapeutic strategy to help dispose of excess stored lipid and ameliorate the
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