D5689
DM 235
solid
Synonym(s):
1-Benzoyl-4-propanoylpiperazine, Sunifiram
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About This Item
Empirical Formula (Hill Notation):
C14H18N2O2
CAS Number:
Molecular Weight:
246.30
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
form
solid
color
white
solubility
H2O: 24 mg/mL
SMILES string
CCC(=O)N1CCN(CC1)C(=O)c2ccccc2
InChI
1S/C14H18N2O2/c1-2-13(17)15-8-10-16(11-9-15)14(18)12-6-4-3-5-7-12/h3-7H,2,8-11H2,1H3
InChI key
DGOWDUFJCINDGI-UHFFFAOYSA-N
Biochem/physiol Actions
DM 235 (Sunifiram) is a potent nootropic agent.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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D Manetti et al.
Journal of medicinal chemistry, 43(23), 4499-4507 (2000-11-23)
Several 4-substituted 1-acylpiperazines, obtained by molecular simplification of 4-substituted 1,4-diazabicyclo[4.3.0]nonan-9-ones, have been synthesized and tested in vivo on the mouse passive avoidance test, to evaluate their nootropic activity. The results show that, apparently, an N-acylpiperazine group can mimic the 2-pyrrolidinone
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