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A5894

Sigma-Aldrich

Antipyrylazo III

~95%

Synonym(s):

3,6-Bis(4-antipyrylazo)-4,5-dihydroxy-2,7-naphthalenedisulfonic acid disodium salt

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About This Item

Empirical Formula (Hill Notation):
C32H26N8Na2O10S2
CAS Number:
14918-39-9
Molecular Weight:
792.71
Beilstein:
956469
EC Number:
238-988-2
MDL number:
MFCD00042700
UNSPSC Code:
12171500
PubChem Substance ID:
24891032

Assay

~95%

technique(s)

titration: suitable

suitability

suitable for determination of calcium (method in Anal. Chim. Acta, 71, 343 (1974))

SMILES string

[Na+].[Na+].CN1N(c2ccccc2)C(=O)C(\N=N\c3c(O)c4c(O)c(\N=N\C5=C(C)N(C)N(c6ccccc6)C5=O)c(cc4cc3S([O-])(=O)=O)S([O-])(=O)=O)=C1C

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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M Irving et al.
The Journal of general physiology, 93(4), 585-608 (1989-04-01)
Antipyrylazo III was introduced into frog cut twitch fibers (17-19 degrees C) by diffusion. After action potential stimulation, the change in indicator absorbance could be resolved into two components that had different time courses and wavelength dependences. The first component
Luba Ginzburg et al.
Journal of neurochemistry, 104(1), 140-146 (2008-01-05)
We previously observed that gangliosides GM2, GM1, and GM3 inhibit Ca2+-uptake via the sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) in neurons and in brain microsomes. We now systematically examine the effect of various gangliosides and their analogs on Ca2+-uptake via SERCA and
Regulation of Ca2+ release from the ryanodine receptor of sarcoplasmic reticulum.
G H O'Sullivan et al.
Biochemical Society transactions, 23(2), 358S-358S (1995-05-01)
C E Gavin et al.
Analytical biochemistry, 192(1), 44-48 (1991-01-01)
The metallochromic indicator antipyrylazo III can be used for the rapid and convenient monitoring of Mn2+ transport in biological systems. The apparent KD of the Mn-antipyrylazo III complex in buffered 150 mM KCl (pH 7.2 at 20 degrees C) is
A Struk et al.
Cell calcium, 23(1), 23-32 (1998-05-07)
Fura-2 is one of the most frequently used fluorescent Ca indicator dyes; yet it has limitations in tracking large intracellular Ca transients due to its high affinity for Ca. Since high affinity is of advantage when small Ca changes are
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