Tentagel beads are functionalized polystyrene-polyethylene glycol (PS-PEG) beads that may be used in the development of combinatorial libraries for high throughput analysis.
Journal of combinatorial chemistry, 10(5), 726-731 (2008-07-29)
Cysteine-rich peptides are valued as tags for biarsenical fluorophores and as environmentally important reagents for binding toxic heavy metals. Due to the inherent difficulties created by cysteine, the power of one-bead one-compound (OBOC) libraries has never been applied to the
Archiv der Pharmazie, 330(4), 109-111 (1997-04-01)
Peptides from small combinatorial libraries, covalently attached to polymeric TentaGel beads, can be directly sequenced using amino acid analysis. For libraries with restricted diversity, generated by the split-mix synthesis method, the amino acids on a selected single bead identified by
Journal of combinatorial chemistry, 11(1), 91-102 (2008-12-09)
The one-bead one-compound (OBOC) combinatorial library method enables the rapid generation and screening of millions of discrete chemical compounds on beads. Most of the OBOC screening methods require the library compounds to remain tethered to the bead during screening process.
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