The renal concentrating ability declines with age in humans and animals. Studies suggest that the concentrating defect is due to a decrease in renal vasopressin sensitivity. With ageing, expression of the renal vasopressin V2 receptor in rat is impaired; the
Problemy endokrinologii, 33(6), 65-67 (1987-11-01)
The capacity of testosterone administered in vivo in the form of testosterone propionate (TP), to modify chromosome integrity and a search for certain conditions under which the hormone manifested cytogenetic activity, were determined. TP was administered at a single dose
Journal of chromatography, 377, 23-33 (1986-04-25)
A gas chromatographic-mass spectrometric (GC-MS) method using three analytes to detect and confirm the administration to equine male castrates of veterinary pro-drugs based upon esters of testosterone is described. The method involves extraction of steroid conjugates from horse urine by
Testosterone controls the synthesis of seminal vesicle protein F in male rats by regulating the cellular concentration of its mRNA (mRNAF). Phage lambda recombinants have been isolated containing the complete F gene. In addition plasmids have been constructed containing cDNAF
Female zebra finches can be induced to develop a male-like song system by being exposed to a steroid as nestlings. After subsequent testosterone treatment they develop song whose quality depends on age and duration of early steroid treatment. This study
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