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NISTRM8398

Human DNA for whole-genome variant assessment (Daughter of Utah/European Ancestry)

NIST SRM 8398

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About This Item

UNSPSC Code:
41116107
NACRES:
NA.24
Pricing and availability is not currently available.

grade

certified reference material

Quality Level

100

form

liquid

manufacturer/tradename

NIST®

application(s)

genomic analysis

Related Categories

General description

This reference material consists of a female whole human genome sample of Utah/European ancestry. A unit of RM 8398 consists of a vial containing human genomic DNA extracted from a single large growth of human lymphoblastoid cell line GM12878 (labeled as HG-001). The vial contains approximately 10μg of genomic DNA, and the DNA is in TE buffer (10 mM TRIS, 1 mM EDTA, pH 8.0).

SRM 8398_cert

SRM 8398_SDS

Application

Standard Reference Material (SRM) intended for validation, optimization, and process evaluation purposes. Used to assess performance of human genome sequencing variant calling by obtaining estimates of true positives, false positives, and false negatives.
Sequencing applications could include whole genome sequencing, whole exome sequencing, and more targeted sequencing such as gene panels. This genomic DNA is intended to be analyzed in the same way as any other sample a lab would process and analyze extracted DNA.

Features and Benefits

  • RM 8398 is from a human lymphoblastoid cell line and is intended for research use.
  • Details of expiration date, stability, homogeneity, and storage and use instructions are provided on NIST certificate.

Legal Information

NIST is a registered trademark of National Institute of Standards and Technology

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

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Questions

1–2 of 2 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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