44577

Doxycycline hyclate

≥98.0% (TLC)

• Synonym(s): Doxycycline hydrochloride hemiethanolate hemihydrate
• Empirical Formula (Hill Notation): C₂₂H₂₄N₂O₈ · HCl · 0.5H₂O · 0.5C₂H₆O
• CAS Number: 24390-14-5
• Molecular Weight: 512.94
• Beilstein: 5702728
• MDL number: MFCD07357237
• UNSPSC Code: 51101500
• PubChem Substance ID: 329756520

Properties

• biological source: synthetic
• Assay: ≥98.0% (TLC)
• form: powder
• impurities: ≤5% water; ≤7% ethanol
• color: faintly yellow to yellow
• solubility: H₂O: 50 mg/mL, clear, yellow-green
• antibiotic activity spectrum: Gram-negative bacteria; Gram-positive bacteria; mycoplasma; parasites
• Mode of action: protein synthesis | interferes
• SMILES string: Cl[H].Cl[H].[H]O[H].CCO.C[C@@H]1C2[C@H](O)C3[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]3(O)C(O)=C2C(=O)c4c(O)cccc14.C[C@@H]5C6[C@H](O)C7[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]7(O)C(O)=C6C(=O)c8c(O)cccc58
• InChI: 1S/2C22H24N2O8.C2H6O.2ClH.H2O/c2*1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;1-2-3;;;/h2*4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31);3H,2H2,1H3;2*1H;1H2/t2*7-,10?,14?,15-,17-,22-;;;;/m00..../s1
• InChI key: HALQELOKLVRWRI-ZVACAFRPSA-N

Description

General description

Chemical structure: tetracycline

Biochem/physiol Actions

Mode of Action: Doxycycline hyclate inhibits the inflammatory response to the Lyme Disease Spirochete Borrelia burgdorferi.

Activity Spectrum: Effective against a broad spectrum inhibitor of matrix metalloproteinases in vivo.

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

This product has been replaced by D9891-SIGMA | Doxycycline hyclate ≥98% (TLC)