Proceedings of the National Academy of Sciences of the United States of America, 110(46), 18549-18554 (2013-10-31)
The adaptor protein Numb has been implicated in the switch between cell proliferation and differentiation made by satellite cells during muscle repair. Using two genetic approaches to ablate Numb, we determined that, in its absence, muscle regeneration in response to
The Journal of physiology, 590(21), 5349-5359 (2012-07-11)
Circulating ATP possesses unique vasomotor properties in humans and has been hypothesized to play a role in vascular control under a variety of physiological conditions. However, the primary downstream signalling mechanisms underlying ATP-mediated vasodilatation remain unclear. The purpose of the
Phytomedicine : international journal of phytotherapy and phytopharmacology, 19(12), 1051-1058 (2012-08-15)
Danshen (Salviae Miltiorrhizae Radix) and Gegen (Puerariae Lobatae Radix) have been widely used in treating cardiovascular diseases for thousands of years in China. The present study was carried out to evaluate the effects of a Danshen and Gegen decoction (DG)
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(10), 4614-4622 (2013-03-08)
After G-protein-coupled receptor activation and signaling at the plasma membrane, the receptor complex is often rapidly internalized via endocytic vesicles for trafficking into various intracellular compartments and pathways. The formation of signaling endosomes is recognized as a mechanism that produces
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 30(3), 687-701 (2012-08-03)
Mitoxanthrone (MX) is an anthracenedione antineoplastic agent. Whether this drug and other related compounds have any effects on ion currents in osteoclasts remains largely unclear. In this study, the effects of MX and other related compounds on inwardly rectifying K(+)
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