8.07484

Polyethylene glycol

300, for synthesis

• Synonym(s): Poly(ethylene glycol), Polyethylene glycol 300, Polyglycol, Polyethylene oxide, Polyoxy ethylene, PEG 300, PEG
• Linear Formula: H(OCH₂CH₂)_nOH
• CAS Number: 25322-68-3
• MDL number: MFCD00081839
• UNSPSC Code: 13111021
• EC Index Number: 500-038-2
• NACRES: NA.22

Properties

• vapor pressure: <0.1 hPa ( 20 °C)
• Quality Level: 200
• form: liquid
• autoignition temp.: 370 °C
• potency: 28000 mg/kg LD₅₀, oral (Rat); >20000 mg/kg LD₅₀, skin (Rabbit)
• pH: 4-7 (20 °C, 100 g/L in H₂O)
• bp: >220 °C/1013 hPa (decomposes)
• mp: -15--10 °C
• transition temp: flash point 220 °C
• density: 1.13 g/cm³ at 20 °C
• storage temp.: 2-30°C
• SMILES string: C(CO)O
• InChI: 1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
• InChI key: LYCAIKOWRPUZTN-UHFFFAOYSA-N

Description

Application

• In vitro ventricular shunt material testing model: A study developed an in vitro testing model for ventricular shunt materials, highlighting the utility of Polyethylene Glycol (PEG) as an antifouling coating, potentially improving shunt performance in clinical settings (Prindeze et al., 2024).


• Antibacterial and anti-inflammatory properties in hydrogels: Research on GelMA-PEG hydrogels incorporated with Imidazolium Poly(ionic liquids) microspheres demonstrated enhanced antibacterial and anti-inflammatory properties, suggesting applications in medical coatings and drug delivery systems (Zhou et al., 2024).


• Bone regeneration scaffolds: A study described the development of a Gellan Gum, Polyethylene Glycol, and Hydroxyapatite composite scaffold, enhanced with Ginseng derived Compound K, which offers potential applications in bone regeneration and tissue engineering (Thangavelu et al., 2024).


• Uniform Polyethylene Glycol synthesis: A comprehensive review discussed the advances and challenges in achieving uniform Polyethylene Glycol (PEG), which is critical for its consistency in various industrial and pharmaceutical applications (Bento et al., 2024).


• AI-Driven optimization of electrospun scaffolds: A study utilized artificial intelligence to optimize PCL/PEG electrospun scaffolds, significantly enhancing in vivo wound healing capabilities, highlighting its potential for medical textiles and tissue engineering applications (Virijević et al., 2024).

Linkage

Replaces: PX1286A-2; PX1286A

Analysis Note

Hydroxyl value: 356 - 394
Density (d 20 °C/ 4 °C): 1.125 - 1.127
Average molecular mass: 285 - 315
Identity (IR): passes test

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): 281.5 °F - closed cup
• Flash Point(C): 138.6 °C - closed cup