1.08622

3,3′,5,5′-Tetramethylbenzidine

GR for analysis

• Synonym(s): 3,3′,5,5′-Tetramethylbenzidine
• Empirical Formula (Hill Notation): C₁₆H₂₀N₂
• CAS Number: 54827-17-7
• Molecular Weight: 240.34
• MDL number: MFCD00007748
• UNSPSC Code: 12352116
• EC Index Number: 259-364-6
• NACRES: NA.05

Properties

• Quality Level: 100
• form: solid
• mp: 166-170 °C
• bulk density: 430 kg/m³
• storage temp.: 15-25°C
• InChI: 1S/C16H20N2/c1-9-5-13(6-10(2)15(9)17)14-7-11(3)16(18)12(4)8-14/h5-8H,17-18H2,1-4H3
• InChI key: UAIUNKRWKOVEES-UHFFFAOYSA-N

Description

Application

• Effect of incubation time on nanozyme-catalyzed oxidation of 3,3′,5,5′-tetramethylbenzidine over silver nanoparticles.: This study investigates the influence of incubation time on the nanozyme-catalyzed oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB) using silver nanoparticles. It highlights the kinetic parameters essential for optimizing the nanozyme activity and potential applications in biosensing and environmental monitoring (Hormozi Jangi et al., 2023).


• Tetramethylbenzidine: An Acoustogenic Photoacoustic Probe for Reactive Oxygen Species Detection.: This research explores the use of TMB as a photoacoustic probe for detecting reactive oxygen species (ROS). It demonstrates TMB′s effectiveness in producing a photoacoustic signal upon reacting with various ROS, showcasing its potential in biological and medical diagnostics (Bresolí-Obach et al., 2020).


• Investigation of vapochromism of 3,3′,5,5′-tetramethylbenzidine-tetrasilicicfluormica intercalation compounds through visible diffuse reflection and powder X-ray diffraction.: This paper examines the vapochromic properties of TMB intercalated in tetrasilicicfluormica using visible diffuse reflection and X-ray diffraction techniques. It reveals insights into the structural changes and potential applications in vapor sensing technologies (Kinoshita & Ishimaru, 2023).


• The determination of the cholinesterase activity using 3,3′,5,5′-tetramethylbenzidine as an indicator.: This study introduces a new method for determining cholinesterase activity using TMB as an indicator. The method provides high sensitivity, reliability, and reproducibility, making it suitable for biochemical analyses and pharmaceutical applications (Koval′ska et al., 2021).


• A facile photothermometric sensor of acid phosphatase based on CoOOH nanozymes-mediated 3,3′,5,5′-tetramethylbenzidine photothermal system.: This article presents a novel photothermometric sensor for acid phosphatase detection. It leverages CoOOH nanozymes and TMB to create a photothermal effect, providing a dual-mode detection system with applications in clinical diagnostics (Wei et al., 2021).

Analysis Note

Assay (perchloric acid titration): ≥ 99 %
Identity (IR-spectrum): conforms
Melting range: 166 - 170 °C
Loss on Drying (105°C): ≤ 0.2 %

Safety Information

• Pictograms: GHS07,GHS08
• Signal Word: Warning
• Hazard Statements: H302 - H351 - H413
• Precautionary Statements: P202 - P264 - P273 - P280 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 4 - Carc. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable