1.02994

Sorbitol

liquid, (sorbitol syrup, crystallizing), EMPROVE^® ESSENTIAL, Ph. Eur., BP, USP, E 420

• Synonym(s): D-Sorbitol, Karion, D-Glucitol
• Empirical Formula (Hill Notation): C₆H₁₄O₆
• CAS Number: 50-70-4
• Molecular Weight: 182.17
• Beilstein: 1721899
• MDL number: MFCD00004708
• UNSPSC Code: 12352201
• E Number: E420

Properties

• Agency: BP; Ph. Eur.; USP
• Quality Level: 500
• vapor density: <1 (vs air)
• vapor pressure: <0.1 mmHg ( 25 °C)
• product line: EMPROVE^® ESSENTIAL
• form: liquid; viscous liquid
• pH: 6 (20 °C in H₂O, 50% solution)
• mp: 98-100 °C (lit.)
• density: 1.3 g/cm³
• application(s): liquid formulation; pharmaceutical
• storage temp.: 15-25°C
• SMILES string: OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO
• InChI: 1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m1/s1
• InChI key: FBPFZTCFMRRESA-JGWLITMVSA-N

Description

General description

Whether suspensions, emulsions or solutions – oral liquid dosage forms offer a number of advantages: They allow for individual dosing, are easy to swallow and are suitable for pediatric or geriatric applications. On the other hand, formulators face considerable challenges concerning solubility, API stability in aqueous systems, or taste that can often make a decisive difference. Our large product portfolio covers all excipients required for oral liquid formulation, as solvents and surfactants, flavors, ph adjustments and buffers, preservatives and viscosity enhancers.
As part of our EMPROVE^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Sorbitol is a sugar alcohol which is frequently used as sweetener in oral liquid pharmaceutical formulations, as well as bulking agent, sugar substitute or humectant in cosmetics and food and beverage.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1