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870818M

Avanti

N-arachidonoylglycine

Avanti Research™ - A Croda Brand 870818M, methylene chloride solution

Synonym(s):

methylene chloride solution

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10 MG
€106.00

€106.00

Estimated to ship on07 May 2025

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10 MG
€106.00

About This Item

Empirical Formula (Hill Notation):
C22H35NO3
CAS Number:
179113-91-8
Molecular Weight:
361.52
MDL number:
MFCD03791313
UNSPSC Code:
12352211
NACRES:
NA.25

€106.00

Estimated to ship on07 May 2025

Request a Bulk Order

form

methylene chloride solution

packaging

pkg of 1 × 1 mL (870818M-10mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 870818M

lipid type

neutral glycerides
neutral lipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

O=C(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)NCC(O)=O

InChI

1S/C22H35NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21(24)23-20-22(25)26/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-20H2,1H3,(H,23,24)(H,25,26)/b7-6-,10-9-,13-12-,16-15-

InChI key

YLEARPUNMCCKMP-DOFZRALJSA-N

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General description

N-arachidonoylglycine (NAgly) is an endogenous ligand and a signaling lipid. It belongs to the eicosanoid family.[1] NAgly is a natural ligand to activate G-protein coupled receptor, namely GPR18.[2][3] It is found in rat brain and spinal cord.[3]

Biochem/physiol Actions

N-arachidonoylglycine (NAgly) exhibits analgesic effects.[3]

Packaging

2 mL Amber Glass Sealed Ampule (870818M-10mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H336,H351

Hazard Classifications

Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Central nervous system

WGK

WGK 2

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH Annex XVII (Restriction List)

CAS No.

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Identification of N-arachidonylglycine as the endogenous ligand for orphan G-protein-coupled receptor GPR18
Kohno M, et al.
Biochemical and Biophysical Research Communications, 347(3), 827-832 (2006)
N-Amino acid linoleoyl conjugates: anti-inflammatory activities
Burstein S, et al.
Bioorganic & Medicinal Chemistry Letters, 22(2), 872-875 (2012)
S M Huang et al.
The Journal of biological chemistry, 276(46), 42639-42644 (2001-08-24)
In mammals, specific lipids and amino acids serve as crucial signaling molecules. In bacteria, conjugates of lipids and amino acids (referred to as lipoamino acids) have been identified and found to possess biological activity. Here, we report that mammals also
Resolution of inflammation by N-arachidonoylglycine
Burstein S H, et al.
Journal of Cellular Biochemistry, 112(11), 3227-3233 (2011)
S H Burstein et al.
Prostaglandins & other lipid mediators, 61(1-2), 29-41 (2000-04-29)
In addition to the well studied hydrolytic metabolism of anandamide, a number of oxidative processes are also possible. Several routes somewhat analogous to the metabolism of free arachidonic acid have been reported. These involve mediation by various lipoxygenases and COX-2
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