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840101C

Avanti

Egg PA

Avanti Research™ - A Croda Brand

Synonym(s):

L-α-phosphatidic acid (Egg, Chicken) (sodium salt)

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25 MG
€149.00

€149.00

Estimated to ship on08 April 2025

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25 MG
€149.00

About This Item

CAS Number:
383907-53-7
MDL number:
MFCD00672609
UNSPSC Code:
12352211
NACRES:
NA.25

€149.00

Estimated to ship on08 April 2025

Request a Bulk Order

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (840101C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

concentration

10 mg/mL (840101C-25mg)

lipid type

phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

SMILES string

[Na+].[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCC\C=C/CCCCCCCC)COC(=O)CCCCCCCCCCCCCCC)O

InChI

1S/C37H71O8P.Na/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-37(39)45-35(34-44-46(40,41)42)33-43-36(38)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;/h17-18,35H,3-16,19-34H2,1-2H3,(H2,40,41,42);/q;+1/p-1/b18-17-;/t35-;/m1./s1

InChI key

PPYXMAJBOKWTQX-RYRMQHSSSA-M

General description

Phosphatidic acid (PA) is synthesized by the action of phospholipase D (PLD) on glycerophospholipids and by phosphorylation of diacylglycerol (DAG) by DAG kinase.[1]

Application

Egg PA has been used in SEIPEN binding studies.[2] It is suitable for use in the preparation of liposomes[3] and to deduce different species of phosphatidic acid from egg by liquid chromatography-mass spectroscopy (LC-MS) and least squares spectral resolution (LSSR) analysis.[4]

Biochem/physiol Actions

Phosphatidic acid (PA) contributes to membrane biogenesis by involving in the synthesis of glycerophospholipids like phosphatidylcholine, phosphatidylethanolamine, phosphatidylinositol and phosphatidylserine. PA is implicated in cell signaling.[1]

Packaging

5 mL Clear Glass Sealed Ampule (840101C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

WGK

WGK 3

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH Annex XVII (Restriction List)

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Extension of least squares spectral resolution algorithm to high-resolution lipidomics data
Zeng YX, et al.
Analytica Chimica Acta, 914(8), 35-46 (2016)
The lipid binding pleckstrin homology domain in UNC-104 kinesin is necessary for synaptic vesicle transport in Caenorhabditis elegans
Klopfenstein DR and Vale RD
Molecular Biology of the Cell, 15(8), 3729-3739 (2004)
Brain Lipids in Synaptic Function and Neurological Disease: Clues to Innovative Therapeutic Strategies for Brain Disorders (2015)
Human SEIPIN binds anionic phospholipids
Yan R, et al.
Developmental Cell, 47(2), 248-256 (2018)
Xianping Li et al.
Infection and immunity, 80(1), 429-440 (2011-11-16)
Aspergillus fumigatus is the most prevalent airborne fungal pathogen that induces serious infections in immunocompromised patients. Phospholipases are key enzymes in pathogenic fungi that cleave host phospholipids, resulting in membrane destabilization and host cell penetration. However, knowledge of the impact
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