N9005

1-Naphthylamine

97%

• Synonym(s): α-Naphthylamine, 1-Aminonaphthalene
• Linear Formula: C₁₀H₇NH₂
• CAS Number: 134-32-7
• Molecular Weight: 143.19
• Beilstein: 386133
• MDL number: MFCD00004016
• UNSPSC Code: 12352100
• PubChem Substance ID: 57654469
• NACRES: NA.22

Properties

• Assay: 97%
• form: solid
• color: light tan to purple
• bp: 301 °C (lit.)
• mp: 47-50 °C (lit.)
• density: 1.114 g/mL at 25 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: Nc1cccc2ccccc12
• InChI: 1S/C10H9N/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7H,11H2
• InChI key: RUFPHBVGCFYCNW-UHFFFAOYSA-N

Description

General description

α-Naphthylamine, a naphthalene substituted by an amino group is an organic dye used as a detection reagent in the synthesis of novel azo dyes.

Application

1-Naphthylamine has been used in the synthesis of Pitnot-2, an inactive analog of clathrin inhibitor Pitstop 2.
It can also be used as a starting material to synthesize:

• [(S)-HY-Phos], a novel chiral phosphine-phosphoramidite ligand for use in rhodium-catalyzed asymmetric hydrogenation of various functionalized olefins.
• N-(naphthalen-1-yl)picolinamide.

Safety Information

• Pictograms: GHS08,GHS07,GHS09
• Signal Word: Danger
• Hazard Statements: H302,H350,H411
• Precautionary Statements: P202 - P264 - P270 - P273 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 1A
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves