Decades of research implicates perfectionism in depressive symptoms. Yet, inconsistent findings, underpowered studies, and the tendency for researchers to assume one direction of influence have clouded understanding of whether perfectionism is a vulnerability factor for depressive symptoms, a complication of
The use of a cholinergic fluorescent probe for the study of the receptor proteolipid.
Little has been known about the demographic and clinical features of the melancholic subtype of major depressive disorder (MDD) in Chinese patients. This study examined the frequency of melancholia in Chinese MDD patients and explored its demographic and clinical correlates
Biochemistry and cell biology = Biochimie et biologie cellulaire, 65(6), 529-535 (1987-06-01)
The kinetics of the hydrolysis of butyrylthiocholine by horse serum butyrylcholinesterase (acylcholine acylhydrolase; BuChE; EC 3.1.1.8) exhibit an activation phenomenon at high substrate concentrations. At least two mechanistic models can account for the enzyme kinetics: one assumes the binding of
We investigated the molecular mechanisms and the binding site location for the fluorophor crystal violet (CrV), a noncompetitive antagonist of the nicotinic acetylcholine receptor (AChR). To this end, radiolabeled competition binding, fluorescence spectroscopy, Schild-type analysis, patch-clamp recordings, and molecular dynamics
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