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Sigma-Aldrich

Resomer® LG 824 S, Poly(L-lactide-co-glycolide)

ester terminated, Lactide: Glycolide 82:18, lactide:glycolide 82:12

Synonym(s):

Resomer® LG 824 S, PLGA

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About This Item

Linear Formula:
HO[C3H4O2]n[C2H2O2]mCH3
CAS Number:
UNSPSC Code:
12162002
NACRES:
NA.23

Quality Level

form

solid

feed ratio

lactide:glycolide 82:12

viscosity

1.7-2.6 dL/g

mp

157-164 °C

transition temp

Tg 54-60 °C

storage temp.

2-8°C

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General description

Resomer® LG 824 S, Poly(L-lactide-co-glycolide) (PLGA), is a semicrystalline, biocompatible, bioresorbable and biodegradable material with high porosity and high surface area. It can be processed by a variety of techniques such as electrospinning, electrospraying and wet spinning.

Application

PLGA can be used in the formation of a membrane for medical applications. It can also be used as a scaffold in tissue engineering.

Legal Information

RESOMER is a registered trademark of Evonik Rohm GmbH

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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In vitro biocompatibility of bioresorbable polymers: poly (L, DL-lactide) and poly (L-lactide-co-glycolide)
Ignatius AA and Claes LE
Biomaterials, 17(8), 831-839 (1996)
Influences of tensile load on in vitro degradation of an electrospun poly (l-lactide-co-glycolide) scaffold
Li P, et al.
Acta Biomaterialia, 6(8), 2991-2996 (2010)
Poly (l-lactide-co-glycolide) biodegradable microfibers and electrospun nanofibers for nerve tissue engineering: an in vitro study
Bini TB, et al.
J. Mater. Sci., 41(19), 6453-6459 (2006)
Electrospun poly (L-lactide-co-glycolide) biodegradable polymer nanofibre tubes for peripheral nerve regeneration
Bini TB, et al.
Nanotechnology, 15(11), 1459-1459 (2004)
Poly (L-lactide-co-glycolide) microporous membranes for medical applications produced with the use of polyethylene glycol as a pore former
Krok M and Pamula E
Journal of Applied Polymer Science, 125(S2), E187-E199 (2012)

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