68571
Aminomethyl ChemMatrix® resin
0.50-0.70 mmol/g loading (amine)
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About This Item
UNSPSC Code:
12352200
NACRES:
NA.22
Recommended Products
product line
ChemMatrix®
form
crystals
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
particle size
100-200 mesh
capacity
0.50-0.70 mmol/g loading (amine)
application(s)
peptide synthesis
functional group
amine
storage temp.
2-8°C
General description
Aminomethyl ChemMatrix® resin is a polyethyleneglycol (PEG)-based resin, composed of highly cross-linked primary ether bonds, therefore the resin is chemically and mechanically stable in a broad range of solvents. It has good loading properties when compared to other PEG resins due to its availability in free-flowing powder form. This resin is also more effective than polystyrene resins in the synthesis of hydrophobic or highly structured polypeptides.
Application
Aminomethyl ChemMatrix® resin can be used as efficient support in solid-phase peptide synthesis (SPPS). It is also used as a starting material to synthesize dihydrolipoyl-supported polymer, which is used as an efficient and recyclable reducing agent for the reduction of disulfide compounds.
Legal Information
ChemMatrix is a registered trademark of Matrix Innovation, Inc.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Convenient supported recyclable material based on dihydrolipoyl-residue for the reduction of disulfide derivatives
Bienvenu C, et al.
Tetrahedron Letters, 51(25), 3309-3311 (2010)
Solid-phase peptide synthesis using acetonitrile as a solvent in combination with PEG-based resins
Gerardo A Acosta, et al.
Journal of Peptide Science, 15(10), 629-633 (2009)
Polyethyleneglycol-based resins as solid supports for the synthesis of difficult or long peptides
Beatriz G, et al.
International Journal of Peptide Research and Therapeutics, 13(1-2), 265-270 (2007)
ChemMatrix for complex peptides and combinatorial chemistry.
Garcia-Ramos Y, et al.
Journal of Peptide Science, 16(12), 675-678 (2010)
Articles
ChemMatrix® is a proprietary, 100% PEG (polyethylene glycol) based resin from PCAS BioMatrix.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
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