49560
L-Glutamic acid dimethyl ester hydrochloride
≥99.0% (anhydrous basis material, AT)
Synonym(s):
L-Glu(OMe)OMe·HCl
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About This Item
Linear Formula:
CH3COOCH2CH2CH(NH2)COOCH3 · HCl
CAS Number:
Molecular Weight:
211.64
Beilstein:
4238829
EC Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.
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Assay
≥99.0% (anhydrous basis material, AT)
optical activity
[α]20/D +26.0±1°, c = 5% in H2O
reaction suitability
reaction type: solution phase peptide synthesis
impurities
~2% water
application(s)
peptide synthesis
storage temp.
2-8°C
SMILES string
Cl.COC(=O)CC[C@H](N)C(=O)OC
InChI
1S/C7H13NO4.ClH/c1-11-6(9)4-3-5(8)7(10)12-2;/h5H,3-4,8H2,1-2H3;1H/t5-;/m0./s1
InChI key
MFUPLHQOVIUESQ-JEDNCBNOSA-N
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Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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D Vicent et al.
Diabetes research and clinical practice, 27(1), 27-30 (1995-01-01)
The dimethyl ester of L-glutamic acid (GME) stimulates insulin release in isolated pancreatic islets and may represent a novel experimental tool in the study of non-insulin-dependent diabetes. In the present study, GME was found both to stimulate insulin secretion and
D Bosco et al.
The American journal of physiology, 268(3 Pt 1), C611-C618 (1995-03-01)
We used a hemolytic plaque assay for insulin to determine whether the same pancreatic B cells respond to D-glucose, 2-amino-bicyclo[2,2,1]heptane-2-carboxylic acid (BCH) and the association of this nonmetabolized analogue of L-leucine with either the monomethyl ester of succinic acid (SME)
P Harikumar
Biochemistry and molecular biology international, 30(6), 1005-1011 (1993-08-01)
A procedure for the preparation of intact membrane vesicles from kidney cortex lysosomes is reported. Highly purified preparations of lysosomes were isolated from rat and buffalo kidney cortex by Percoll density gradient centrifugation. The lysosomal membrane vesicles were prepared by
Effect of glutamate dimethyl ester and glutamate diethyl ester in delaying the onset of convulsions induced by pentylenetetrazol and strychnine.
A S Abdul-Ghani et al.
Biochemical pharmacology, 31(19), 3144-3146 (1982-10-01)
G N Akoev et al.
Journal of comparative physiology. A, Sensory, neural, and behavioral physiology, 168(6), 647-652 (1991-06-01)
1. The effects of excitatory amino acid antagonists on synaptic transmission in the ampullae of Lorenzini of the skate Raja clavata were studied. 2. At concentrations of 10(-3) to 10(-6) M. L-glutamic acid diethylester (GDEE) and L-glutamic acid dimethylester (GDME)
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