Skip to Content
Merck
All Photos(2)

Documents

366633

Sigma-Aldrich

1-(Phenylsulfonyl)indole

98%

Synonym(s):

1-(Benzenesulfonyl)indole, Benzenesulfonic acid indolide, NSC 237040, NSC 683530

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C14H11NO2S
CAS Number:
40899-71-6
Molecular Weight:
257.31
MDL number:
MFCD00134318
UNSPSC Code:
12352100
PubChem Substance ID:
24862680
NACRES:
NA.22

Assay

98%

mp

78-80 °C (lit.)

SMILES string

O=S(=O)(c1ccccc1)n2ccc3ccccc23

InChI

1S/C14H11NO2S/c16-18(17,13-7-2-1-3-8-13)15-11-10-12-6-4-5-9-14(12)15/h1-11H

InChI key

VDWLCYCWLIKWBV-UHFFFAOYSA-N

Application

1-(Phenylsulfonyl)indole may be used in the preparation of 2-acyl-1-(phenylsulfonyl)indoles. It may be used in the synthesis of starting reagent required for the synthesis of the potentially useful intermediate, 1-(phenylsulfonyl)indol-3-yl trifluoromethanesulfonate (triflate).
Reactant for preparation of:
  • Antiplasmodial agents
  • Antifungal agents
  • Anti HIV-1 agents
  • Agonists of the histamine H4 receptor
  • Antibacterial agents
  • Camalexin analogs
  • CDK inhibitors and cytotoxic agents
  • Histone Deacetylase inhibitors

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Synthesis of 1-(phenylsulfonyl) indol-3-YL trifluoromethanesulfonate.
Conway SC and Gribble GW.
Heterocycles, 30(1), 627-633 (1990)
A direct lithiation route to 2-acyl-1-(phenylsulfonyl) indoles.
Jiang J and Gribble GW.
Synthetic Communications, 32(13), 2035-2040 (2002)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service