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Sigma-Aldrich

Undecanoic δ-lactone

98%

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About This Item

Empirical Formula (Hill Notation):
C11H20O2
CAS Number:
710-04-3
Molecular Weight:
184.28
EC Number:
211-915-1
MDL number:
MFCD00006650
UNSPSC Code:
12352100
PubChem Substance ID:
24857524
NACRES:
NA.22

Assay

98%

refractive index

n20/D 1.459 (lit.)

bp

152-155 °C/10.5 mmHg (lit.)

density

0.969 g/mL at 25 °C (lit.)

SMILES string

CCCCCCC1CCCC(=O)O1

InChI

1S/C11H20O2/c1-2-3-4-5-7-10-8-6-9-11(12)13-10/h10H,2-9H2,1H3

InChI key

YZRXRLLRSPQHDK-UHFFFAOYSA-N

Gene Information

human ... CYP1A2(1544)

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General description

Undecanoic δ-lactone has been found to be best substarte for good substrates for lactonase from Sulfolobus islandicus (SisLac).

Application

Undecanoic δ-lactone has been used as substrate to investigate the activities of stimulated and nonstimulated human serum paraoxonase (PON1) samples.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Hazard Classifications

Eye Irrit. 2

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

312.8 °F

Flash Point(C)

156 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Julien Hiblot et al.
PloS one, 7(10), e47028-e47028 (2012-10-17)
A new member of the Phosphotriesterase-Like Lactonases (PLL) family from the hyperthermophilic archeon Sulfolobus islandicus (SisLac) has been characterized. SisLac is a native lactonase that exhibits a high promiscuous phosphotriesterase activity. SisLac thus represents a promising target for engineering studies
S Billecke et al.
Drug metabolism and disposition: the biological fate of chemicals, 28(11), 1335-1342 (2000-10-19)
It is well established that human serum paraoxonase (PON1) catalyzes the hydrolysis of organophosphate insecticides and nerve agents, as well as that of a number of aromatic carboxylic acid esters. Our laboratory has recently found a new class of PON1

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