Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

188611

Sigma-Aldrich

3-[2-(Diethylamino)ethyl]-7-hydroxy-4-methylcoumarin hydrochloride

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C16H21NO3 · HCl
CAS Number:
15776-59-7
Molecular Weight:
311.80
EC Number:
239-872-4
MDL number:
MFCD00006855
UNSPSC Code:
12352100
PubChem Substance ID:
24851169
NACRES:
NA.22

form

solid

mp

284-287 °C (dec.) (lit.)

functional group

amine
ester

SMILES string

Cl[H].CCN(CC)CCC1=C(C)c2ccc(O)cc2OC1=O

InChI

1S/C16H21NO3.ClH/c1-4-17(5-2)9-8-14-11(3)13-7-6-12(18)10-15(13)20-16(14)19;/h6-7,10,18H,4-5,8-9H2,1-3H3;1H

InChI key

RLJNKMCFVQMDFR-UHFFFAOYSA-N

Application

3-[2-(Diethylamino)ethyl]-7-hydroxy-4-methylcoumarin hydrochloride was used in the synthesis of:
  • novel metal-free and zinc phthalocyanines with four 3-[(2-diethylamino)ethyl]-7-oxo-4-methylcoumarin dye groups via cyclotetramerization[1]
  • 3-(2-diethylaminoethyl)-4-methyl-7-substituted coumarins, having antifungal activities against Botrytis cinerea[2]

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
08605AU
03406HN
01814BI

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Synthesis and characterization of novel phthalocyanines bearing quaternizable coumarin.
Cakici H, et al.
Polyhedron, 27(18), 3625-3630 (2008)
Synthesis and in vitro evaluation of novel 1, 2, 4-triazole derivatives as antifungal agents.
Kokil GR, et al.
Letters in Drug Design & Discovery, 7(1), 46-49 (2010)
Doyoung Kwon et al.
Molecular pharmacology, 96(5), 641-654 (2019-09-08)
The hepatic endoplasmic reticulum (ER)-anchored monotopic proteins, cytochromes P450 (P450s), are enzymes that metabolize endobiotics (physiologically active steroids and fatty acids), as well as xenobiotics including therapeutic/chemotherapeutic drugs, nutrients, carcinogens, and toxins. Alterations of hepatic P450 content through synthesis, inactivation
Gönül Yenilmez Çiftçi et al.
Journal of fluorescence, 25(6), 1819-1830 (2015-10-01)
In the present work, 3-[2-(diethylamino)ethyl]-7-oxy-4-methylcoumarin substituted cyclotriphosphazene (4) and cyclotetraphosphazene (5) derivatives were synthesized by the reactions of hexachlorocyclotriphosphazene (1) or octachlorocyclotetraphosphazene (2) with 3-[2-(diethylamino)ethyl]-7-hydroxy-4-methylcoumarin (3) for the first time. The quaternized cationic (6 and 7) and zwitterionic (8 and

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service