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Merck

1463304

USP

Nikotinbitartratdihydrat

United States Pharmacopeia (USP) Reference Standard

Synonym(e):

(−)-Nikotin -hydrogen-tartrat (Salz) Dihydrat

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About This Item

Empirische Formel (Hill-System):
C10H14N2 · 2C4H6O6 · 2H2O
CAS-Nummer:
Molekulargewicht:
498.44
UNSPSC-Code:
41116107
NACRES:
NA.24

Qualität

pharmaceutical primary standard

API-Familie

nicotine

Hersteller/Markenname

USP

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

InChI

1S/C17H15ClN2O3/c1-9(2)16(22)19-11-4-5-14(21)12(8-11)17-20-13-7-10(18)3-6-15(13)23-17/h3-9,20H,1-2H3,(H,19,22)/b17-12-

InChIKey

YGMGVHYZWYRTJJ-ATVHPVEESA-N

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Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Nicotine bitartrate dihydrate USP reference standard for use in specified quality tests and assays.

Also used to prepare standard, system suitability, sensitivity, and standard stock solution for assay, identification, performance test, and impurity analysis according to the given below monographs of United States Pharmacopeia (USP):
  • Nicotine
  • Nicotine Polacrilex
  • Nicotine Transdermal System

Hinweis zur Analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Sonstige Hinweise

Sales restrictions may apply.

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Piktogramme

Skull and crossbonesHealth hazard

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 1 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - STOT RE 1

Lagerklassenschlüssel

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Nicotine Transdermal System
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 42(2), 3153-3153 (2021)
Nicotine Polacrilex
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 44(1), 3156-3156 (2020)
Brandon J Henderson et al.
The Journal of general physiology, 143(1), 51-66 (2014-01-01)
Chronic exposure to nicotine up-regulates high sensitivity nicotinic acetylcholine receptors (nAChRs) in the brain. This up-regulation partially underlies addiction and may also contribute to protection against Parkinson's disease. nAChRs containing the α6 subunit (α6* nAChRs) are expressed in neurons in
Nicotine
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 46(5) (2022)
Cheng Xiao et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(9), 3734-3746 (2015-03-06)
The glutamatergic subthalamic nucleus (STN) exerts control over motor output through nuclei of the basal ganglia. High-frequency electrical stimuli in the STN effectively alleviate motor symptoms in movement disorders, and cholinergic stimulation boosts this effect. To gain knowledge about the

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