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1301007

USP

Guaifenesin

United States Pharmacopeia (USP) Reference Standard

Synonym(e):

Guajakol-Glycerin-Ether, 3-(2-Methoxyphenoxy)-propan-1,2-diol, Guaifenesin, Guajakolglycerolether

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About This Item

Empirische Formel (Hill-System):
C10H14O4
CAS-Nummer:
93-14-1
Molekulargewicht:
198.22
MDL-Nummer:
MFCD00016873
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329749971
NACRES:
NA.24

Qualität

pharmaceutical primary standard

API-Familie

guaifenesin

Hersteller/Markenname

USP

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

SMILES String

COc1ccccc1OCC(O)CO

InChI

1S/C10H14O4/c1-13-9-4-2-3-5-10(9)14-7-8(12)6-11/h2-5,8,11-12H,6-7H2,1H3

InChIKey

HSRJKNPTNIJEKV-UHFFFAOYSA-N

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Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Guaifenesin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Acetaminophen and Diphenhydramine Citrate Tablets
  • Dyphylline and Guaifenesin Oral Solution
  • Dyphylline and Guaifenesin Tablets
  • Guaifenesin
  • Guaifenesin and Codeine Phosphate Oral Solution
  • Guaifenesin Capsules
  • Guaifenesin Compounded Injection, Veterinary

Hinweis zur Analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Sonstige Hinweise

Sales restrictions may apply.

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Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H302

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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2-Methoxyphenol for synthesis

Sigma-Aldrich

8.18339

2-Methoxyphenol

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Robert R Fayzullin et al.
Journal of pharmaceutical sciences, 103(10), 3176-3182 (2014-08-06)
The solubility of 3-(2-methoxyphenoxy)-propane-1,2-diol, the well-known chiral drug guaifenesin 1, in water has been investigated by means of polythermal and isothermal approaches. It was found that the solubilities of racemic and enantiomeric diols rac- and (R)-1 depend strongly on temperature.
Clinical inquiries. Is guaifenesin safe during pregnancy?
Roberto Silva et al.
The Journal of family practice, 56(8), 669-670 (2007-08-03)
William Storms et al.
Current allergy and asthma reports, 9(2), 101-106 (2009-02-13)
Mucus in the airways is a complex mixture of water, lipids, glycoproteins, sugars, and electrolytes that serves as a lubricant for the epithelium. The efficient flow of respiratory mucus is a first level of immune defense that requires an appropriate
Stephen Bennett et al.
Journal of alternative and complementary medicine (New York, N.Y.), 10(6), 967-969 (2005-01-28)
Ephedrine and guaifenesin are herbal supplements that have experienced increased use over the past decade. Ephedrine has been used as a stimulant and weight-loss product, guaifenesin as an expectorant and cough suppressant; both are found in combination in many antitussives
Manujendra Ray et al.
Hospital practice (1995), 37(1), 60-63 (2010-09-30)
Adverse drug reactions lead to a significant number of hospital admissions each year and thus contribute to the overall financial burden of health care. Some of these drug reactions are allergic responses. As the overall predictability of allergic responses to
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