BP1229

Capecitabin

British Pharmacopoeia (BP) Reference Standard

• Synonym(e): 5′-Deoxy-5-fluor-N-[(pentyloxy)-carbonyl]-cytidin, Ro-9-1978
• Empirische Formel (Hill-System): C₁₅H₂₂FN₃O₆
• CAS-Nummer: 154361-50-9
• Molekulargewicht: 359.35
• MDL-Nummer: MFCD00930626
• UNSPSC-Code: 41116107
• NACRES: NA.24

Eigenschaften

• Qualität: pharmaceutical primary standard
• Qualitätsniveau: 100
• API-Familie: capecitabine
• Form: powder
• Haltbarkeit: limited shelf life, expiry date on the label
• Hersteller/Markenname: BP
• Anwendung(en): pharmaceutical; pharmaceutical small molecule
• Format: neat
• Lagertemp.: 2-8°C
• SMILES String: O[C@H]1[C@@H](O)[C@H](N2C(N=C(NC(OCCCCC)=O)C(F)=C2)=O)O[C@@H]1C
• InChI: 1S/C15H22FN3O6/c1-3-4-5-6-24-15(23)18-12-9(16)7-19(14(22)17-12)13-11(21)10(20)8(2)25-13/h7-8,10-11,13,20-21H,3-6H2,1-2H3,(H,17,18,22,23)/t8-,10-,11-,13-/m1/s1
• InChIKey: GAGWJHPBXLXJQN-UORFTKCHSA-N
• Angaben zum Gen: human ... TYMS(7298)

Beschreibung

Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Capecitabine BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Capecitabine Tablets

Biochem./physiol. Wirkung

Capecitabine is an anti-cancer drug, a prodrug of doxifluridine, metabolized to 5-fluorouracil at the tumor site. The activation of capecitabine follows a pathway with three enzymatic steps and two intermediary metabolites, 5′-Deoxy-5-fluorocytidine (5′-DFCR) and 5′-Deoxy-5-fluorouridine (5′-DFUR), to form 5-fluorouracil.

Verpackung

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Sonstige Hinweise

Sales restrictions may apply.

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Danger
• H-Sätze: H341,H350,H360FD
• P-Sätze: P201 - P308 + P313
• Gefahreneinstufungen: Carc. 1B - Muta. 2 - Repr. 1B
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable