SRP6099

GSTM1 from mouse

recombinant, expressed in E. coli, ≥95% (SDS-PAGE)

• Synonym(e): GST 1-1, GST class-mu1, Glutathione S-transferase Mu 1, pmGT10
• UNSPSC-Code: 12352200
• NACRES: NA.32

Eigenschaften

• Biologische Quelle: mouse
• Rekombinant: expressed in E. coli
• Assay: ≥95% (SDS-PAGE)
• Form: liquid
• Mol-Gew.: 25.9 kDa
• Verpackung: pkg of 100 μg
• NCBI-Hinterlegungsnummer: P10649
• UniProt-Hinterlegungsnummer: P10649
• Versandbedingung: dry ice
• Lagertemp.: −70°C
• Angaben zum Gen: mouse ... GSTM1(14862)

Beschreibung

Allgemeine Beschreibung

GSTM1 (glutathione S-transferase μ 1) belongs to the superfamily of glutathione-S-transferases. It belongs to the μ class of soluble GSTs. GSTM1 is strongly expressed in the kidneys.

Biochem./physiol. Wirkung

Members of GST (glutathione S-transferase) superfamily are responsible for the metabolism of various reactive oxygen species and xenobiotics. GSTM1 (GST μ 1) plays a significant role in vascular homeostasis. Humans with null allele, GSTM1(0), are at increased risks for colon and lung cancers, hypertension, and atherosclerosis, and have higher DNA changes in atherosclerotic lesions of the abdominal aorta.

Physikalische Form

1 mg/mL solution in PBS (pH 7.4) containing 5 mM Glutathione

Angaben zur Herstellung

Centrifuge the vial prior to opening.

Sonstige Hinweise

MPMILGYWNV RGLTHPIRML LEYTDSSYDE KRYTMGDAPD FDRSQWLNEK FKLGLDFPNL PYLIDGSHKI TQSNAILRYL ARKHHLDGET EEERIRADIV ENQVMDTRMQ LIMLCYNPDF EKQKPEFLKT IPEKMKLYSE FLGKRPWFAG DKVTYVDFLA YDILDQYRMF EPKCLDAFPN LRDFLARFEG LKKISAYMKS SRYIATPIFS KMAHWSNK

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable