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Merck

SRP4039

Sigma-Aldrich

Fgf-2 from rat

recombinant, expressed in E. coli, ≥97% (SDS-PAGE), ≥97% (HPLC)

Synonym(e):

FGB-b, FGF-2, Fibroblast Growth Factor-basic, HBGF-2, Prostatropin

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About This Item

UNSPSC-Code:
12352202
NACRES:
NA.32

Biologische Quelle

rat

Rekombinant

expressed in E. coli

Assay

≥97% (HPLC)
≥97% (SDS-PAGE)

Form

lyophilized

Wirksamkeit

<0.2 ng/mL

Mol-Gew.

~16.3 kDa

Verpackung

pkg of 50 μg

Lagerbedingungen

avoid repeated freeze/thaw cycles

Verunreinigungen

endotoxin, tested

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Lagertemp.

−20°C

Angaben zum Gen

rat ... Fgf2(54250)

Allgemeine Beschreibung

Fibroblast growth factor-2 (FGF-2) is a basic heparin binding growth factor and a profibrotic factor. The recombinant mouse FGF-2 is a single, non-glycosylated chain containing 145 amino acids and having a molecular weight of 16.3kDa.

Biochem./physiol. Wirkung

Fibroblast growth factor-2 (FGF-2) stimulates the proliferation of a wide variety of cells including mesenchymal, neuroectodermal and endothelial cells.

Physikalische Form

Lyophilized from 1 mg/ml solution after extensive dialysis against 20 mM phosphate buffer, pH 7.4 and 130 mM NaCl.

Rekonstituierung

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in sterile water to 0.1–1 mg/mL.

Lagerklassenschlüssel

13 - Non Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

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Liu Y
Journal of the American Heart Association, 4(7), e001598-e001598 (2015)
FGF-18, a novel member of the fibroblast growth factor family, stimulates hepatic and intestinal proliferation.
Hu MC
Molecular and Cellular Biology, 18(10), 6063-6074 (1998)
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International journal of oncology, 47(1), 91-96 (2015-05-09)
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Developmental biology, 332(1), 166-176 (2009-06-02)
Previous studies of the developing lens have shown that Notch signaling regulates differentiation of lens fiber cells by maintaining a proliferating precursor pool in the anterior epithelium. However, whether Notch signaling is further required after the onset of fiber cell
Larisa Antonova et al.
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Tissue-engineered vascular grafts are widely tested as a promising substitute for both arterial bypass and replacement surgery. We previously demonstrated that incorporation of VEGF into electrospun tubular scaffolds from poly(3-hydroxybutyrate-co-3-hydroxyvalerate)/poly(ε-caprolactone) enhances formation of an endothelial cell monolayer. However, an overdose

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