SML3356

Gefarnate

≥98% (HPLC)

• Synonym(e): (4E,​8E)​-5,​9,​13-​Trimethyl-​4,​8,​12-​tetradecatrienoic acid (2E)​-​3,​7-​dimethyl-​2,​6-​octadien-​1-​yl ester, (E,E,E)-4,8,12-Tetradecatrienoic acid, 5,9,13-trimetyl-, 3,7-dimetyl-2,6-octadienyl ester, Geranyl farnesylacetate
• Empirische Formel (Hill-System): C₂₇H₄₄O₂
• CAS-Nummer: 51-77-4
• Molekulargewicht: 400.64
• MDL-Nummer: MFCD00129086
• UNSPSC-Code: 51111800

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: liquid
• Lagerbedingungen: desiccated
• Farbe: colorless to beige
• Lagertemp.: −20°C
• SMILES String: CC(C)=CCC/C(C)=C/COC(CC/C=C(CC/C=C(CCC=C(C)C)\C)\C)=O
• InChI: 1S/C27H44O2/c1-22(2)12-8-14-24(5)16-10-17-25(6)18-11-19-27(28)29-21-20-26(7)15-9-13-23(3)4/h12-13,16,18,20H,8-11,14-15,17,19,21H2,1-7H3/b24-16+,25-18+,26-20+
• InChIKey: ZPACYDRSPFRDHO-ROBAGEODSA-N

Beschreibung

Biochem./physiol. Wirkung

Gefarnate is an anti-ulcer drug that stimulates gastric mucin secretion. Also gefarnate increase secretion of mucin-like glycoprotein in rabbit conjunctival tissue. It appears to be effective in animal dry-eye models. It is approved in Japan, where it is used to treat gastritis and gastric ulcer. Gefarnate is structurally similar to anti-ulcer drug teprenone (geranyl farnesylacetate), which induces expression of HSP70, HSPB8, and HSPB1.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable