SML2791

SBI-797812

≥98% (HPLC)

• Synonym(e): 1-[4-(8-Oxa-3-azabicyclo[3.2.1]octane-3-sulfonyl)-phenyl]-3-pyridin-4-ylmethylurea, N-[4-(8-Oxa-3-azabicyclo[3.2.1]oct-3-ylsulfonyl)phenyl]-N′-(4-pyridinylmethyl)-urea
• Empirische Formel (Hill-System): C₁₉H₂₂N₄O₄S
• CAS-Nummer: 2237268-08-3
• Molekulargewicht: 402.47
• MDL-Nummer: MFCD32197237
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 2 mg/mL, clear
• Lagertemp.: 2-8°C
• SMILES String: O=C(NC1=CC=C(S(=O)(N(C2)C[C@H]3O[C@@H]2CC3)=O)C=C1)NCC4=CC=NC=C4

Beschreibung

Biochem./physiol. Wirkung

SBI-797812 is a cell penetrant and potent activator of nicotinamide phosphoribosyltransferase (NAMPT) that increases intracellular levels of NMN and NAD+ in cells. SBI-797812 blocks binding of inhibitors to NAMPT and shifts the reaction equilibrium towards NMN formation. It elevates levels of NAD+ in mice liver.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable