SML1487

ABT-089 dihydrochloride

≥98% (HPLC)

• Synonym(e): 2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine dihydrochloride, Pozanicline dihydrochloride
• Empirische Formel (Hill-System): C₁₁H₁₆N₂O · 2HCl
• CAS-Nummer: 161416-61-1
• Molekulargewicht: 265.18
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329825916
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder
• Optische Aktivität: [α]/D +20 to +30°, c = 1 in methanol
• Farbe: white to beige
• Löslichkeit: H₂O: 20 mg/mL, clear
• Lagertemp.: 2-8°C
• SMILES String: CC1=C(OC[C@@H]2CCCN2)C=CC=N1.[H]Cl.[H]Cl
• InChI: 1S/C11H16N2O.2ClH/c1-9-11(5-3-6-12-9)14-8-10-4-2-7-13-10;;/h3,5-6,10,13H,2,4,7-8H2,1H3;2*1H/t10-;;/m0../s1
• InChIKey: UGVSESCRKJTJAK-XRIOVQLTSA-N

Beschreibung

Biochem./physiol. Wirkung

ABT-089 (Pozanicline) is a subtype-selective neuronal nicotinic receptor partial agonist binding primarily to the α4β2 and also α6β2 subtypes. It has been investigated for alleviating symptoms of nicotine withdrawal including cognitive deficits and anxiety.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302
• P-Sätze: P264 - P270 - P301 + P312 - P501
• Gefahreneinstufungen: Acute Tox. 4 Oral
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable