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SML1078

Sigma-Aldrich

4-Bromo-Resveratrol

≥98% (HPLC)

Synonym(e):

5-[(1E)-2-(4-Bromophenyl)ethenyl]-1,3-benzenediol

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About This Item

Empirische Formel (Hill-System):
C14H11BrO2
CAS-Nummer:
1224713-90-9
Molekulargewicht:
291.14
MDL-Nummer:
MFCD00238583
UNSPSC-Code:
12352200
PubChem Substanz-ID:
329825458
NACRES:
NA.77

Assay

≥98% (HPLC)

Form

powder

Lagerbedingungen

protect from light

Farbe

, white to yellow to brown

Löslichkeit

DMSO: 20 mg/mL, clear

Lagertemp.

2-8°C

SMILES String

OC1=CC(/C=C/C2=CC=C(Br)C=C2)=CC(O)=C1

InChI

1S/C14H11BrO2/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,16-17H/b2-1+

InChIKey

NCJVLKFAQIWASE-OWOJBTEDSA-N

Allgemeine Beschreibung

4-Bromo-Resveratrol blocks the activity of human sirtuin 1 (sirt1) and sirt3 by binding to C-site and another active site pocket.

Biochem./physiol. Wirkung

4-Bromo-Resveratrol is a resveratrol analog that potently inhibits Sirt1 and Sirt3.

Leistungsmerkmale und Vorteile

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Sonstige Hinweise

light sensitive

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Viniferin ≥95% (LC/MS-ELSD)

Sigma-Aldrich

SMB00074

Viniferin

Resveratrol A phenolic product found in both grape skins and wines.

Sigma-Aldrich

554325

Resveratrol

Pterostilben ≥97% (HPLC), solid

Sigma-Aldrich

P1499

Pterostilben

Polydatin ≥95% (HPLC)

Sigma-Aldrich

15721

Polydatin

trans-Resveratrol United States Pharmacopeia (USP) Reference Standard

USP

1602105

trans-Resveratrol

Nicotinamid ≥98% (HPLC), powder

Sigma-Aldrich

N3376

Nicotinamid

JC-1 solid

Sigma-Aldrich

T4069

JC-1

Dansylcadaverin ≥97% (TLC)

Sigma-Aldrich

D4008

Dansylcadaverin

Resveratrol analytical standard

Supelco

34092

Resveratrol

trans-Stilben 96%

Sigma-Aldrich

139939

trans-Stilben

Giang Thi Tuyet Nguyen et al.
Chemistry & biology, 20(11), 1375-1385 (2013-11-12)
Sirtuins are protein deacetylases regulating aging processes and various physiological functions. Resveratrol, a polyphenol found in red wine, activates human Sirt1 and inhibits Sirt3, and it can mimic calorie restriction effects, such as lifespan extension in lower organisms. The mechanism
Mengling Li et al.
Redox biology, 36, 101632-101632 (2020-08-31)
Recent research suggests that melatonin (Mel), an endogenous hormone and natural supplement, possesses anti-proliferative effects and can sensitise cells to anti-cancer therapies. Although shikonin (SHK) also possesses potential anti-cancer properties, the poor solubility and severe systemic toxicity of this compound
Liang-Jun Wang et al.
Biochemical pharmacology, 162, 154-168 (2018-11-11)
Albendazole (ABZ) is a microtubule-targeting anthelmintic that acts against a variety of human cancer cells, but the dependence of its cytotoxicity on non-mitotic effect remains elusive. Thus, we aimed to explore the mechanistic pathway underlying the cytotoxicity of ABZ in

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