SML0813

BRD56491

≥98% (HPLC)

• Synonym(e): 2-(4-Methylphenyl)-4H-benzo[h]chromen-4-one, 2-(4-Methylphenyl)-4H-naphtho[1,2-b]pyran-4-one
• Empirische Formel (Hill-System): C₂₀H₁₄O₂
• CAS-Nummer: 14756-26-4
• Molekulargewicht: 286.32
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 2 mg/mL, clear (warmed)
• Lagertemp.: 2-8°C

Beschreibung

Biochem./physiol. Wirkung

BRD56491 is a nontoxic enhancer of reactive oxygen species (ROS) that strongly elevates markers of oxidative stress without causing cell death. However, combining BRD56491 with nontoxic doses of the glutathione synthesis inhibitor L-buthionine sulfoximine did lead to cell death in a variety of cancer cell lines. BRD56491 can be used to create a more oxidizing cell state and aid in studies of cancer cell lines resilient to induced increases in ROS levels.

Sicherheitshinweise

• H-Sätze: H413
• P-Sätze: P273 - P501
• Gefahreneinstufungen: Aquatic Chronic 4
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable