SML0045

Salvianolic acid A hydrate

≥98% (HPLC)

• Synonym(e): Dan phenolic acid A hydrate
• Empirische Formel (Hill-System): C₂₆H₂₂O₁₀ · xH₂O
• CAS-Nummer: 96574-01-5
• Molekulargewicht: 494.45 (anhydrous basis)
• MDL-Nummer: MFCD20527310
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329825115
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: yellow
• Löslichkeit: H₂O: ≥19 mg/mL
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• SMILES String: O.OC(=O)[C@@H](Cc1ccc(O)c(O)c1)OC(=O)\C=C\c2ccc(O)c(O)c2\C=C\c3ccc(O)c(O)c3
• InChI: 1S/C26H22O10.H2O/c27-18-7-2-14(11-21(18)30)1-6-17-16(4-9-20(29)25(17)33)5-10-24(32)36-23(26(34)35)13-15-3-8-19(28)22(31)12-15;/h1-12,23,27-31,33H,13H2,(H,34,35);1H2/b6-1+,10-5+;/t23-;/m1./s1
• InChIKey: XFUSRNNWIRPEDG-FYLUTCCGSA-N

Beschreibung

Anwendung

Salvianolic acid A hydrate may be used in cell signaling studies.
Salvianolic acid A hydrate has been used as rosmarinic acid derivative for the inhibition of DNA polymerase e in human cell lines.

Biochem./physiol. Wirkung

Salvianolic acid A acts as scavengers of reactive oxygen species, reduces the adherence of leukocytes to endothelial cells, inhibits matrix metalloproteinases and inflammation. It has cardioprotective effects as it suppresses apoptosis, reduces lipid peroxidation in damaged cardiac tissue and decreases the leakage of lactic acid dehydrogenase.

Salvianolic acid A is cell protective antioxidant originally isolated from Salvia. It has been found to attenuate PDGF-induced ROS formation in hepatic stellate cells and protected against isoproterenol-induced myocardial damage in rats.

Sicherheitshinweise

• Lagerklassenschlüssel: 13 - Non Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable