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Merck

SCP0139

Sigma-Aldrich

Caspase 8 Substrate, fluorogenic

≥95% (HPLC), lyophilized

Synonym(e):

Ac-VETD-AMC

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About This Item

Empirische Formel (Hill-System):
C30H39N5O12
Molekulargewicht:
661.66
UNSPSC-Code:
12352202
NACRES:
NA.32

product name

Caspase 8 Substrate, fluorogenic,

Assay

≥95% (HPLC)

Form

lyophilized

Zusammensetzung

Peptide Content, ≥67%

Lagerbedingungen

protect from light

Lagertemp.

−20°C

Angaben zum Gen

human ... CASP8(841)

Amino Acid Sequence

Ac-Val-Glu-Thr-Asp-AMC

Anwendung

Fluorogenic caspase 8 substrate has been used to measure caspase 8 activity in Jurkat cell lysates.

Biochem./physiol. Wirkung

The peptide Ac-Val-Glu-Thr-Asp-AMC, or Ac-VETD-AMC, is a fluorogenic, modified peptide substrate for caspase 8.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

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Ali, S.M., et al.
The American Journal of Physiology, 278, R763-R769 (2000)
Functional intersection of Human Defensin 5 with the TNF receptor pathway
WuyuanLu Erikde Leeuw
Febs Letters, 558(10) (2014)
T L Yue et al.
The Journal of biological chemistry, 274(3), 1479-1486 (1999-01-09)
TL1 is a recently discovered novel member of the tumor necrosis factor (TNF) cytokine family. TL1 is abundantly expressed in endothelial cells, but its function is not known. The present study was undertaken to explore whether TL1 induces apoptosis in
Mikhail G Akimov et al.
Biomolecules, 10(2) (2020-02-16)
Cholines acylated with unsaturated fatty acids are a recently discovered family of endogenous lipids. However, the data on the biological activity of acylcholines remain very limited. We hypothesized that acylcholines containing residues of arachidonic (AA-CHOL), oleic (Ol-CHOL), linoleic (Ln-CHOL), and
Natalia M Gretskaya et al.
European journal of pharmacology, 883, 173346-173346 (2020-07-14)
Glioblastoma (GBM) is an aggressive and lethal form of brain cancer with a high invasion capacity and a lack of effective chemotherapeutics. Retinoid bexarotene (BXR) inhibits the neurospheroidal colony formation and migration of primary glioblastoma cells but has side effects.

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