SAE0219

Mucin Degradation Enzyme

for preparative digestions, powder

Eigenschaften

• Qualitätsniveau: 200
• Form: powder
• Haltbarkeit: 2 yr (retest)
• Lagerbedingungen: protect from light
• Versandbedingung: dry ice
• Lagertemp.: -10 to -25°C

Beschreibung

Allgemeine Beschreibung

Mucin Degradation Enzyme is a metalloprotease useful for digesting heavily O-glycosylated mucin proteins. This product is made for preparative scale digestions of viscous material that is dense with mucin-type glycoproteins.

Anwendung

For use as a sample preparation tool in research and discovery. Used for proteolytic degradation of mucin-dense tissues to allow for downstream processing.

Biochem./physiol. Wirkung

The Mucin Degradation enzyme is a mutated form of a protease that specifically recognizes densely glycosylated mucins and mucin-domains, and proteolytically cleaves the peptide backbone. In nature this presumably enhances the virulence of the pathogenic microbe, but in the laboratory is a useful way of accessing molecular structures in tissues normally shielded by mucins.

Sicherheitshinweise

• Lagerklassenschlüssel: 13 - Non Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable