SAB5702242

Anti-CD70 Antibody, clone 7F4S5, Rabbit Monoclonal

• Synonym(e): CD27L, CD27LG, TNFSF7
• UNSPSC-Code: 12352203
• NACRES: NA.46

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Materialien: colorless
• Klon: 7F4S5, monoclonal
• Form: liquid
• Speziesreaktivität: human
• Konzentration: 1 mg/mL
• Methode(n): flow cytometry: 1:100 - 1:800; western blot: 1:500 - 1:2000
• Farbe: colorless
• Isotyp: IgG
• UniProt-Hinterlegungsnummer: P32970
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... CD70(970)

Beschreibung

Allgemeine Beschreibung

CD70 is a member of the TNF family whose expression is upregulated on DCs upon maturation. Its only receptor, CD27, is expressed on T cells and NK cells. The CD70/CD27 pathway promotes effector CD8+ T cells responses (by sustaining survival of CTLs) and influences polarization of CD4+ T cells, as it represents an alternative IL-12-independent pathway of Th1 priming and suppresses effector Th17 function.

Immunogen

PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.

Recombinant protein of human CD70.

Anwendung

WB, FC

Sicherheitshinweise

• Piktogramme: GHS07,GHS09
• Signalwort: Warning
• H-Sätze: H317,H411
• P-Sätze: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• Gefahreneinstufungen: Aquatic Chronic 2 - Skin Sens. 1
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3