SAB5701953

Anti-Phospho-IκBα-S32 antibody produced in rabbit

• UNSPSC-Code: 12352203
• NACRES: NA.43

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: liquid
• Speziesreaktivität: human, mouse
• Konzentration: 0.63 mg/mL
• Methode(n): western blot: 1:500-1:2000
• UniProt-Hinterlegungsnummer: P25963
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pSer32)
• Angaben zum Gen: human ... NFKBIA(4792)

Beschreibung

Allgemeine Beschreibung

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

Immunogen

A phospho specific peptide corresponding to residues surrounding S32 of human NFKBIA.

Physikalische Form

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable