SAB5700526

Anti-Phospho-Tau-S519/T522 antibody produced in rabbit

• Synonym(e): DDPAC, FTDP-17, MAPT, MAPTL, MSTD, MTBT1, MTBT2, PPND, PPP1R103, TAU, Tau
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: 32-45; 78- 80
• Speziesreaktivität: mouse, human
• Konzentration: 0.72 mg/ml
• Methode(n): immunofluorescence: 1:50-1:100; western blot: 1:500-1:2000
• UniProt-Hinterlegungsnummer: P10636
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pSer519/pThr522)
• Angaben zum Gen: human ... MAPT(4137)

Beschreibung

Allgemeine Beschreibung

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer′s disease, Pick′s disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Immunogen

A phospho specific peptide corresponding to residues surrounding S519/T522 of human Tau

Physikalische Form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Lagerung und Haltbarkeit

Store at -20℃. Avoid freeze / thaw cycles.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable