SAB5700478

Anti-Phospho-PTPRA-Y789 antibody produced in rabbit

• Synonym(e): HEPTP, HLPR, HPTPA, HPTPalpha, LRP, PTPA, PTPRA, PTPRL2, R-PTP-alpha, RPTPA
• UNSPSC-Code: 12352203
• NACRES: NA.43

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: 89; 90
• Speziesreaktivität: rat, human, mouse
• Konzentration: 0.71 mg/ml
• Methode(n): western blot: 1:500-1:2000
• UniProt-Hinterlegungsnummer: P18433
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pTyr789)
• Angaben zum Gen: human ... PTPRA(5786)

Beschreibung

Allgemeine Beschreibung

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported.

Immunogen

A phospho specific peptide corresponding to residues surrounding Y789 of human PTPRA

Physikalische Form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Lagerung und Haltbarkeit

Store at -20℃. Avoid freeze / thaw cycles.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable