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Merck

SAB5500164

Sigma-Aldrich

Anti-PLAP antibody, Rabbit monoclonal

recombinant, expressed in proprietary host, clone SP15, tissue culture supernatant

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

Rekombinant

expressed in proprietary host

Konjugat

unconjugated

Antikörperform

tissue culture supernatant

Antikörper-Produkttyp

primary antibodies

Klon

SP15, monoclonal

Speziesreaktivität

human (tested)

Methode(n)

immunohistochemistry: 1:100

Isotyp

IgG

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Lagertemp.

2-8°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... ALPP(250)

Allgemeine Beschreibung

Placental alkaline phosphatase (PLAP) or ALPP is a phosphomonoesterase. It is expressed in the placenta and endometrium. The PLAP gene is localized on human chromosome 2q37.1.

Immunogen

Recombinant protein encoding human placental alkaline phosphatase.

Biochem./physiol. Wirkung

Placental alkaline phosphatase (PLAP) or ALPP is a hydrolase, which is involved in the hydrolysis of phosphomonoesters. It has been shown to be a biomarker for ovarian cancer. The protein is expressed in carcinomas such as ovarian adenocarcinoma, dysgerminoma, serous cystadenocarcinoma and undifferentiated carcinoma.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

0.1 ml rabbit monoclonal antibody supplied as tissue culture supernatant in TBS/1% BSA buffer pH 7.5 with less than 0.1% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Genome wide expression profile in human HTR-8/Svneo trophoblastic cells in response to overexpression of placental alkaline phosphatase gene.
Bellazi L
Placenta (2011)
A human monoclonal antibody specific to placental alkaline phosphatase, a marker of ovarian cancer.
Ravenni N
MAbs (2014)
Refined structures of placental alkaline phosphatase show a consistent pattern of interactions at the peripheral site.
Stec B
Acta Crystallographica Section F, Structural Biology and Crystallization Communications (2010)
Cloverleaf skull anomaly and de novo
trisomy 4p
Journal of medical Genetics (1999)
Human placental alkaline phosphatase-mediated hydrolysis correlates tightly with the electrostatic contribution from tail group.
Yang Y
Chemical Biology & Drug Design (2011)

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